Plant breeders can help America re-orient our dominant system of single-crop agriculture toward a multi-crop landscape that is less costly to farmers, better for the environment, helps slow climate change and still yields a profit. But, those efforts are just one part of a complex system that also will require the buy-in of farmers themselves, supported by political will, new agricultural policies and the cooperation of scientists, seed companies, machinery and fertilizer manufacturers, insurance providers, banks and environmental groups.